I was asked by a customer to produce a PowerShell script to iterate over all of the sites in a particular site collection and change the search target to the following address “http://[searchsite]/”. This is the result of that request.
$site = Get—SPSite "http://[site]"     
foreach ($web in $site.Allwebs) {      
    Write—Host "Modifying all search result pages in site ($($web.Url))"       
    $web.AllProperties["SRCH_ENH_FTR_URL"] = http://[searchsite]/     
    $web.update()      
}       
$site.Dispose()
This is based on a larger article I found here, which details a few more options you can set at the same time.
http://mrhodes.net/2010/09/14/set-site-collection-search-settings-by-powershell/